FGF基因家族在哺乳动物卵巢发育中的研究进展

doi:10.11843/j.issn.0366-6964.2017.08.001

摘要/Abstract

摘要：

成纤维细胞生长因子（Fibroblast growth factor，FGF）家族在个体的胚胎发育、卵泡发育、生殖细胞的成熟、能量代谢、器官的发育和形成、组织修复、骨骼发育以及内环境的稳定等多种生物学过程中发挥重要作用。成纤维细胞生长因子家族根据其作用方式分为旁分泌型成纤维细胞生长因子、自分泌型成纤维细胞生长因子和内分泌型成纤维细胞生长因子。各家族的功能各不相同又有所交叉，目前关于该家族的研究主要集中于胚胎发育、动物繁殖以及糖脂代谢等方面。本文主要对哺乳动物卵巢发育过程中成纤维细胞生长因子的研究进行综述，以深入探索卵巢发育的调控机制。

Abstract:

The fibroblast growth factor family plays the important role in a variety of biological processes including embryonic development, follicular development, maturation of the germ cells, energy metabolism, organ formation and development, tissue regeneration, skeletal development and homeostasis, and so on. The FGF family was divided into paracrine FGFs, autocrine FGFs and endocrine FGFs depending on its different modes of action. The functions of FGFs are different while some are overlapped. Now, the researches of FGFs are mainly focused on embryonic development, animal reproduction and glycolipid metabolism. Here the biological functions of FGFs in mammalian ovary development are reviewed, in order to further explore the regulatory mechanism of ovary development.

中图分类号:

S813.1

周梅, 狄冉, 胡文萍, 王翔宇, 刘秋月, 储明星. FGF基因家族在哺乳动物卵巢发育中的研究进展[J]. 畜牧兽医学报, 2017, 48(8): 1373-1380.

ZHOU Mei, DI Ran, HU Wen-ping, WANG Xiang-yu, LIU Qiu-yue, CHU Ming-xing. Research Progress on Fibroblast Growth Factor Gene Family in Mammalian Ovary Development[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2017, 48(8): 1373-1380.

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